Isoniazid-Associated Hepatitis

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منابع مشابه

Severe isoniazid-associated hepatitis--New York, 1991-1993.

In November 1992, the New York State Department of Health was notified of a patient who underwent liver transplantation because of severe hepatitis that developed during the use of isoniazid (INH) preventive therapy (IPT) for latent tuberculous infection. Inquiry at liver transplant centers in New York revealed other patients who had hepatitis attributed to INH. This report summarizes findings ...

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Hepatitis following isoniazid.

V. N., a 30 year old white male was admitted to the Veterans Administration Hospital, Tucson, Arizona on November 16, 1953 for the treatment of pulmonary tuberculosis The diagnosis was first established in 1944 and treatment had not included antimicrobial drugs prior to the present admission. He was considered inactive from 1946 until a positive culture of the sputum was obtained in September 1...

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Immune Thrombocytopenia Associated with Hepatitis A Infection in Children

Hepatitis A infection is usually a self–limited disease during childhood. Autoimmune manifestations are rarely reported among patients with HA infection. We describe a previously healthy 6-yr-old male with acute hepatitis A who developed immune thrombocytopenia.

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Detecting Novel Genetic Variants Associated with Isoniazid-Resistant Mycobacterium tuberculosis

BACKGROUND Isoniazid (INH) is a highly effective antibiotic central for the treatment of Mycobacterium tuberculosis (MTB). INH-resistant MTB clinical isolates are frequently mutated in the katG gene and the inhA promoter region, but 10 to 37% of INH-resistant clinical isolates have no detectable alterations in currently known gene targets associated with INH-resistance. We aimed to identify nov...

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hepatitis-associated aplastic anemia

there is a well-recognized relationship between aplastic anemia and viral hepatitis. clinically apparent hepatitis precedes aplastic anemia by a period of weeks to months. hepatitis is an infrequent cause of aplastic anemia and is usually severe and fatal if untreated. the clinical features and, particularly the response to immunosuppressive therapy strongly suggest that immune mechanisms media...

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ژورنال

عنوان ژورنال: Gastroenterology

سال: 1975

ISSN: 0016-5085

DOI: 10.1016/s0016-5085(19)32599-5